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Brighten your day! Natural serotonin support for a healthy, happy mood and greater mental & emotional wellbeing. read more


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Product overview

Doctor’s Best 5-HTP (100 mg) is just what you need to promote a relaxed and calm mental and emotional state. Formulated using naturally-sourced 5-HTP extracted from the seeds of the Griffonia simplicolia plant, this important precursor molecule to our own natural neurotransmitter serotonin supports a beneficial impact on mood, sleep, carbohydrate cravings and discomfort associated with fatigue.

  • An easy 1 capsule daily dose of 100 mg 5-HTP (5-hydroxy L-tryptophan)
  • Promotes a sense of overall mental and emotional wellbeing
  • Supports healthy sleep regulation, neurotransmitter function and reduced sugar cravings
What is 5-HTP?

5-HTP (5-hydroxy L-tryptophan) is a precursor for the brain neurotransmitter serotonin, known as the feel-good brain chemical. Serotonin in turn is a precursor for the sleep neurotransmitter and hormone melatonin. Low levels of these neurotransmitters can result in mood, sleep, appetite and hormonal imbalances that can leave you feeling quite blue. Supporting a healthy balance of these neurotransmitters by supplementing with 5-HTP as a nutritional precursor helps support restful sleep, positive mood and a better regulated appetite.

Why use 5-HTP over L-Tryptophan?

L-Tryptophan is an essential amino acid found in protein foods that the body uses as a precursor to produce serotonin. However, this process only occurs naturally following enzymatic conversion with tryptophan hydroxylase which converts dietary tryptophan to 5-HTP. However, tryptophan can also be shunted down other biochemical pathways in the body. 5-HTP, in contrast, is already is a form able to easily cross the blood-brain-barrier for the production of serotonin in the central nervous system. In addition, unlike tryptophan which is in competition with other amino acids for absorption, 5-HTP is able to be absorbed easily and directly, with or without the presence of other amino acids.

About Doctor’s Best

Doctor’s Best creates vitamins and supplements using science-based techniques that combine natural ingredients using thoroughly researched and tested methods. Doctor’s Best is committed to transparency and education, and uses only certified cGMP facilities to ensure the highest quality standards are met.


5-HTP (5-hydroxy L-tryptophan) (from Griffonia simplicolia extract) (seed) 100 mg. Other ingredients: Modified cellulose (vegetarian capsule), microcrystalline cellulose and silicon dioxide.

Does not contain: GMO, Gluten, Soy. 100% vegan.

Suggested Use

Recommended intake:

Suggested Adult Use: Take 2 capsules daily, or as recommended by a health practitioner.

  • Not to be used when taking MAO inhibitors, selective serotonin reuptake inhibitors (SSRIs), or other anti-depressant medications. It should also not be used by individuals taking any of the category of medications known as “triptans.”
  • May impair your ability to drive or operate machinery.
  • If pregnant, nursing or taking medications, consult a healthcare practitioner prior to use.
  • Store in a cool dry place.
  • Do not use if safety seal is broken or missing.
  • Keep out of reach of children.
  • Always read the label and use as directed. If symptoms persist see your healthcare practitioner.


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